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Fusidic acid

Image:Fusidic acid.png Fusidic acid is an antibacterialantibioticused particularly for eyeand skininfections. It works by interfering with bacterialproteinsynthesis, specifically by preventing the translocation of the elongation factor G (EF-G) from the ribosome, although it works only on gram-positive bacteria such as Staphylococcusaureus, Streptococcus and Corynebacteriumminutissimum. It was first isolated in 1962from the fungus Fusidiumcoccineum, and later from Mucorramannianus and Isariakogana.

It is delivered as an ointment, a cream or eye drops.

Brand names

  • Fusidin (of Leo in Canada)
  • Fucidin
  • Fucithalmic (of Leo in UK and Denmark)

Reference

  • RxMed Monograph
  • Synthesis of photoreactive fusidic acid analogues for binding studies with elongation factor Gde:Fusidinsäure

hu:Fuzidinsav

Retrieved from "http://en.wikipedia.org/Fusidic_acid"



This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Fusidic+acid Wikipedia article Fusidic acid.

 
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