Libman-Sacks endocarditis

Libman-Sacks endocarditis is a form of nonbacterial endocarditisthat is seen in systemic lupus erythematosus. It was named after American physicians Emanuel Libmanand Benjamin Sacks. It is the most common cardiac manifestation of lupus. The vegetations are formed from strands of fibrin, neutrophils, lymphocytes, and histiocytes. The mitral valveis typically affected, and the vegetations occur on the ventricular surface of the valve. Libman-Sacks lesions rarely produce significant valve dysfunction and the lesions only rarely embolize.

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