Glucose-dependent insulinotropic peptide

{{Protbox codes

  |Symbol=GIP
  |AltSymbols=
  |HGNCid=4270
  |Chromosome=17
  |Locus=q21.3-q22
  |AApro=---
  |Codes=OMIM137240, EntrezGene2695, RefSeqNM_004123, UniProtP09681
  |AApre=153 

}} </table> Glucose-dependent insulinotropic peptide (GIP) is a hormonesecreted by K-cellsin the duodenumof the gastrointestinal tract.

It was formerly called gastrointestinal inhibitory peptide or gastric inhibitory peptide and was believed to neutralize stomach acidto protect the small intestinefrom acid damage as well as reduce the rate at which foodis transferred through the stomach. However, it was discovered that these effects are only achieved with higher-than-normal physiological level, and that these results naturally occur in the body through a similar hormone, secretin.

It is now believed that the function of is to induce insulinsecretion after glucoseis detected in the small intestine. After this discovery, it was given the new name of glucose-dependent insulinotropic peptide, but retained the acronym"GIP."

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Glucose-dependent+insulinotropic+peptide Wikipedia article Glucose-dependent insulinotropic peptide.