Arrhenoblastoma

The arrhenoblastoma is a rare ovarianstromalneoplasmthat secretes testosterone. While it may occur at any age, it is mostly seen in women in the reproductive years. Typically it is unilateral.

The key clinical features of this tumor are related to its endocrine activity. The excessive production of testosterone leads to progressive masculinization in a woman who typically had been normal. Thus the person may experience not only anovulationand amenorrhea, but usually also acneand hirsutism, voice deepening, clitoromegaly, temporal hair recession, and an increase in musculature. On gynecologic ultrasonographya unilateral solid lesion can be seen in the ovary. A serum testosterone level is high.

The treatment consists of surgical removal and the prognosis is generally good as the lesion tends to grow slowly and rarely metastasizes.

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It uses material from the http://en.wikipedia.org/wiki/Arrhenoblastoma Wikipedia article Arrhenoblastoma.