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Asherman's syndrome

{{{Name|Asherman's syndrome}}}
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ICD-10 N85.6
ICD-O: {{{ICDO}}}
ICD-9 621.5
OMIM }}}
MedlinePlus }}}
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DiseasesDB }}}

Asherman's syndrome, also called "uterine synechiae", presents a condition characterized by the presence of scars within the uterine cavity.

Inhaltsverzeichnis

  • 1 Features
  • 2 Diagnosis
  • 3 Treatment
  • 4 Prognosis
  • 5 History
  • 6 External links

Features

The cavity of the uterusis lined by the endometrium. This lining can be traumatized, typically after a dilation and curettage(D&C) done after a miscarriage, abortion, or delivery, and then develops intrauterine scars which can obliterate the cavity to a varying degree. In the extreme, the whole cavity has been scarred and occluded. Even with relatively few scars, the endometrium may fail to respond to estrogensand rests. The patient experiences secondary amenorrheaand becomes infertile. An artificial form of Asherman's syndrome can be surgically induced by uterine ablationin women with uterine bleeding problems in lieu of hysterectomy.

Diagnosis

The history of a pregnancyevent followed by a D&C leading to seconday amenorrhea is typical. Imaging by gynecologic ultrasonographyor hysterosalpingographywill reveal the extent of the scar formation. Hormone studies show normal levels consistent with reproductive function.

Ultrasound is not a reliable method of diagnosing Asherman's Syndrome. Options include HSG (hysterosalpingography) or SHG (sonohysterography). Hysteroscopy is the most reliable. The website at www.ashermans.org gives more detail.


Treatment

Operative hysteroscopyis used for visual inspection of the uterine cavity and dissection of scar tissue.

Prognosis

The extent of scar formation is critical. Small scars can usually be treated with success. Extensive obliteration of the uterine cavity may require several surgical interventions or even be uncorrectable. Patients who carry a pregnancyafter correction of Asherman's syndrome may have an increased risk of having a placentathat invades the uterusmore deeply, leading to complications in placental separation after delivery.

History

It is also known as Fritsch syndrome, or Fritsch-Asherman syndrome per the individuals who described it, Heinrich Fritschand Joseph G. Asherman.

External links

  • Ashermans.org
  • NIH/Medline plus
  • iVillagenl:Syndroom van Asherman
Retrieved from "http://en.wikipedia.org/Asherman%27s_syndrome"



This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Asherman%27s+syndrome Wikipedia article Asherman's syndrome.

 
  All text is available under the terms of the GNU Free Documentation License