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Granulosa cell tumour

{{{Name|Granulosa cell tumour}}}
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ICD-10 {{ICD10
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 ICD9           = 183|
 ICDO           = 8620 |
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 eMedicineSubj  = med |
 eMedicineTopic = 928 |
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}} Granulosa cell tumours (or granulosa-theca) are part of the sex cord-stromal tumourgroup of ovarian neoplasms.

The peak age at which they occur is 50-55 years, but they may occur at any age.

Inhaltsverzeichnis

  • 1 Clinical presentation
  • 2 Histology
  • 3 See also
  • 4 External links

Clinical presentation

Estrogensare produced by functioning tumours, and the clinical presentation depends on the patient's age.

  • If the patient is postmenopausal, she usually presents with abnormal uterine bleeding.
  • If the patient is of reproductiveage, she would present with menometrorrhagia.
  • If the patient has not undergone puberty, isosexual-pseudo-precocitymay be seen.

Histology

The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with blood. Hemoperitoneum is an infrequent but classical presentation. A large variety of histologicalpresentations exists, but they have two key features:

  1. Call-Exner bodies(granulosa cellsarranged haphazardly around a space containing eosinophilicfluid); and
  2. Pale uniform nuclei, often with grooves

See also

  • granulosa cell
  • Sertoli-Leydig cell tumour

External links

  • GPnotebook-46858173
  • Photo of tumor
  • Slides
  • indiandoctors.com
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Retrieved from "http://en.wikipedia.org/Granulosa_cell_tumour"



This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Granulosa+cell+tumour Wikipedia article Granulosa cell tumour.

 
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