Auer rods

Auer rods are seen in the leukemic blasts of acute myelogenous leukemia. Auer rods are clumps of azurophilicgranular material that form elongated needles seen in the cytoplasmof leukemic blasts. They are composed of fused lysosomesand contain peroxidase, lysosomal enzymes, and large crystalline inclusions.

These cytoplasmic inclusions were named by John Auer, an American physiologist (1875-1948).

Reference

• Auer J. Some hitherto undescribed structures found in the large lymphocytes of a case of acute leukaemia. Am J Med Sci 1906;131:1002-1015.

External links

• NIH/Medline (includes image)
• Slides
• University of Utah

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