Dilute Russell viper venom time

Dilute Russell viper venom time is a laboratory test for lupus anticoagulant. Russell's vipervenomdirectly activates factor Xin the patient's plasma. If the lupus anticoagulant (LA) is present, the clotting time is prolonged because the LA binds up the phospholipid. Relatively common deficiencies or inhibitors of factors VII, VIII, IX, XI and XII do not affect the assay.

The dRVVT is thought to be more sensitive than the aPTT for detection of lupus anticoagulants.

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