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HemolysisHemolysis (alternative spelling haemolysis) is the excessive breakdown of red blood cells. When this happens, it may cause a form of anemia, called Hemolytic anemia. Hemolysis caused during blood collectionHemolysis is an important factor in medical tests, as a bloodsample may become hemolysed with prolonged storage or when complications arise during venipuncture. For example, when a blood sample is collected, hemolysis is rare when the collection is straightforward. On occasions when a patient's veins are uncooperative (such as collapsing under the pull of a vacuum from a syringe or a modern vacuum tube), the problem becomes more prevalent. The red cells in the blood are literally smashed on their way through the needle, often due to excessive suction. This results in a poor sample. Hemolysis may cause interference with the test results for a patient, but this is mostly limited to biochemistry tests, such as an elevated potassium. Hemolysis may be caused by one of various medical conditions or during surgical procedures. During intraoperative blood salvage, hemolysis may occur as a result of highly increased levels of suction into the cardiotomy. During the centrifuge process of filling the centrifuge, washing the RBC's with normal saline, and returning them to the patient's blood supply, hemolysis may occur if the centrifuge is set to rotate to quickly (generally more than 500 rpms). Unfortunately, this is unavoidable during some cases involving massive amounts of sudden blood loss because the process of returning patient's cells must be done at an exponentially higher speed to prevent hypotension, pH imbalance, and a number of other hemodynamic & blood level factors.
es:Hemólisis fr:Hémolyse it:Emolisi nl:Hemolyse no:Hemolytisk anemi sv:Hemolytisk anemi tr:Hemoliz zh:???? Categories: Hematology
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