ZAP70 deficiency

ZAP70 deficiency (zeta-chain-associated protein 70 kD) is a rare autosomal recessiveform of severe combined immunodeficiency(SCID) that is characterized by a lack of CD8+ T cellsand the presence of circulating CD4+ T cells that are unresponsive to T-cell receptor(TCR)-mediated stimuli.

External links

• IDR Factfile
• ZAP70base: Mutation registry for autosomal recessive ZAP70 deficiency
• OMIM176947

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/ZAP70+deficiency Wikipedia article ZAP70 deficiency.