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Hypertensive nephropathy

**{{{Name|Hypertensive nephropathy}}}**
[[Image:{{{Image}}}\|190px\|center\|]] {{{Caption\|}}}
ICD-10	I12
ICD-O:	{{{ICDO}}}
ICD-9	403
OMIM	}}}
MedlinePlus	}}}
eMedicine	}}}
DiseasesDB	}}}

Hypertensive nephropathy (or "hypertensive nephrosclerosis", or "Hypertensive renal disease") is a medical condition referring to damage to the kidneydue to chronic high blood pressure.

It should be distinguished from "renovascular hypertension" (I15.0), which is a form of secondary hypertension.

In the kidneys, as a result of benign arterial hypertension, hyaline(pink, amorphous, homogeneous material) accumulates in the wall of small arteries and arterioles, producing the thickening of their walls and the narrowing of the lumens- hyaline arteriolosclerosis. Consequent ischemiawill produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller glomeruliwith different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis. In advanced stages, renal failurewill occur. Functional nephrons have dilated tubules, often with hyaline castsin the lumens.

External links

Photo at Atlas of Pathology
PubMed
Oxford Journals

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