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Frontotemporal dementia

Image:Frontotemporal degeneration.jpg

{{{Name|Frontotemporal dementia}}}
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ICD-9 331.83
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Frontotemporal dementia (FTD) is one of three clinical syndromes associated with frontotemporal lobar degeneration. FTD selectively affects the frontal lobeof the brainand may extend backward to the temporal lobe. There are two main types: Pick's disease, which has been recognised for many years, and Dementia of the Frontal Lobe Type (DFLT), more recently described. The pathologyof these two conditions is different although the clinical manifestations are similar.

The frontal lobe is involved in many aspects of mental function. These include motivation and drive, classifying and categorizing, emotion and personality. Social behaviour is also influenced as is appetite.

Frontal dysfunction may therefore lead to apathy or conversely disinhibition, disordered high level thinking- perseveration, and personality change. The manifestation will depend on which part of the lobe is more affected — dorsolateral or orbitomedial. Many routine dementia assessments do not test the frontal lobe.

Frontotemporal dementia sometimes occurs with Motor neurone disease.

Inhaltsverzeichnis

  • 1 Further reading
  • 2 References
  • 3 See also
  • 4 External links

Further reading

  • A collection of articles about Frontotemporal dementia in the journal Neurology
  • Radin, Lisa. "What If It's Not Alzheimer's: A Caregiver's Guide to Dementia." Prometheus Books. 2003.

References

  • Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF. "Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria." 'Neurology' (1998) 51(6):1546-54. Available: [1]
  • Neary D, Snowden JS, Mann DM. "Classification and description of frontotemporal dementias." Ann N Y Acad Sci (2000) 920:46-51. Available: [2]
  • Kramer JH, Jurik J, Sha SJ, Rankin KP, Rosen HJ, Johnson JK, Miller BL. "Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease." Cogn Behav Neurol. (2003) 16(4):211-8. Available: [3]
  • Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N, Weiner M, Feiwell R, Kramer JH, Miller BL. "Patterns of brain atrophy in frontotemporal dementia and semantic dementia." Neurology (2002) 58(2):198-208. Available: [4]
  • Miller BL, Seeley WW, Mychack P, Rosen HJ, Mena I, Boone K. "Neuroanatomy of the self: Evidence from patients with frontotemporal dementia." Neurology (2001) 57:817-821. Available: [5]

See also

  • Frontotemporal lobar degeneration
  • Pick's disease
  • Semantic dementia
  • Progressive nonfluent aphasia
  • Alzheimer's disease
  • Corticobasal degeneration

External links

  • The Association for Frontotemporal Dementias
  • UCSF Memory and Aging Center - FTD Resourcesand FTD Info
  • Mayo Clinic - FTD Info
  • Pick's Disease Support Group Online
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This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Frontotemporal+dementia Wikipedia article Frontotemporal dementia.

 
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