Frontotemporal lobar degeneration

Image:Frontotemporal degeneration.jpg

Frontotemporal lobar degeneration (FTLD) is a form of dementia. In the over 65 age group it is probably the fourth most common type of dementia after Alzheimer's disease, dementia with Lewy bodiesand vascular dementia. In the below 65 age group it is the second most common cause after Alzheimer's disease.

There are three clinical variants of FTLD:

• frontotemporal dementia (or frontal variant FTLD)
• semantic dementia
• progressive nonfluent aphasia

There are a number of possible pathological findings at post-mortem:

• tauinclusions (either with Pick bodiesor without)
• ubiquitininclusions
• dementia lacking distinctive histology(DLDH)

References

• Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF. "Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria." 'Neurology' (1998) 51(6):1546-54. Available: [1]

See also

• Frontotemporal dementia
• Semantic dementia
• Progressive nonfluent aphasia
• Alzheimer's disease
• Corticobasal degeneration

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Frontotemporal+lobar+degeneration Wikipedia article Frontotemporal lobar degeneration.