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Choriocarcinoma

**{{{Name|Choriocarcinoma}}}**
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ICD-10	(ICD-O9100-9101)
ICD-O:	{{{ICDO}}}
ICD-9
OMIM	}}}
MedlinePlus	}}}
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Choriocarcinoma is a malignant and aggressive cancerof the placenta. It is characterized by early hematogenous spread to the lungs.

Inhaltsverzeichnis

1 Etiology/Epidemiology
2 Symptoms/Signs/Labs
3 Pathology
4 Treatment

Etiology/Epidemiology

It is preceded by

hydatidiform mole(50% of cases)
abortion of ectopic pregnancy(20% of cases)
normal term pregnancy (20-30% of cases)

Symptoms/Signs/Labs

increased β-hCGlevels
vaginal bleeding

Pathology

On light microscopy, there is malignant trophoblasticproliferation without hydropic villi.

Treatment

Choriocarcinoma is one of the tumors that is most sensitive to chemotherapy. The cure rate, even for metastatic choriocarcinoma, is around 90-95%. Virtually everyone without metastases can be cured. Chemotherapy regimen include Methotrexateor dactinomycin.

Hysterectomy(surgical removal of the uterus) can also be offered to patients > 40 years of age or those desiring sterilization. It may be required for those with severe infection and uncontrolled bleeding.

Image:Star of life2.png

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This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Choriocarcinoma Wikipedia article Choriocarcinoma.

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