Detoxication

The major metabolites formed from most drug metabolismare detoxication products. There are two common patterns observed:

1. A drug with potent pharmacological activity is converted to a major metabolite with markedly reduced or no pharmacological activity (e.g., Pentobarbitaland Hydroxypentobarbital)
2. A drug is converted to a metabolite with roughly equivalent or slightly lower pharmacological activity.

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It uses material from the http://en.wikipedia.org/wiki/Detoxication Wikipedia article Detoxication.