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Dose-response curve

A dose-response curve is a simple X-Y graph with X usually being the measured dose (usually in milligrams, micrograms, or gramsper kilogram of body-weight) and Y being the response. Additionally, the graph is typically sigmoidal, with the steepest portion in the middle. The curves are usually qualitative, though they can use quantitativeinformation. The first point along the graph where a response above zero is reached is usually referred to as a threshold-dose. For most beneficial or recreational drugs or substances, the desired effects are found slightly after the threshold dose. After the desired effects the undesired side effects appear and grow stonger as the dose increases. The last point on the dose-response curve is a fatal dose, the average point at which death will occur in humans. The stronger a particular substance is, the steeper this curve will be. In quantitiative situations, the Y-axis usually is designated by percentages, which refer to the percentage of users registering a standard response (which is often death, when the 50% mark refers to LD50).


Interactive dose-response curve

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It uses material from the http://en.wikipedia.org/wiki/Dose-response+curve Wikipedia article Dose-response curve.

 
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